Maternal Ube3a Loss Disrupts Sleep Homeostasis But Leaves Circadian Rhythmicity Largely Intact

Individuals with Angelman syndrome (AS) suffer sleep disturbances that severely impair quality of life. Whether these disturbances arise from sleep or circadian clock dysfunction is currently unknown. Here, we explored the mechanistic basis for these sleep disorders in a mouse model of Angelman synd...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Ehlen, J. Christopher, Jones, Kelly A., Pinckney, Lennisha, Gray, Cloe L., Burette, Susan, Weinberg, Richard J., Evans, Jennifer A., Brager, Allison J., Zylka, Mark J., Paul, Ketema N., Philpot, Benjamin D., DeBruyne, Jason P.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595617/
https://ncbi.nlm.nih.gov/pubmed/26446213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2194-15.2015
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