Rapid and high-efficiency generation of mature functional hepatocyte-like cells from adipose-derived stem cells by a three-step protocol

The generation of functional hepatocytes is a major challenge for regenerative medicine and drug discovery. Here we show a method that facilitates generation of induced functional hepatocytes (iHeps) from adipose-derived stem cells (ADSCs) within 9 days. iHeps express hepatocytic gene programs and d...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Xu, Fen, Liu, Junli, Deng, Jie, Chen, Xiaolei, Wang, Yuan, Xu, Pengchao, Cheng, Lin, Fu, Yanli, Cheng, Fuyi, Yao, Yunqi, Zhang, Yujing, Huang, Meijuan, Yu, Dechao, Wei, Yuquan, Deng, Hongxin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595267/
https://ncbi.nlm.nih.gov/pubmed/26438426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0181-3
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