Immunoexpression of TGF-β/Smad and VEGF-A proteins in serum and BAL fluid of sarcoidosis patients

BACKGROUND: The chronic course of pulmonary sarcoidosis can lead to lung dysfunction due to fibrosis, in which the signalling pathways TGF-β/Smad and VEGF-A may play a key role. METHODS: We evaluated immunoexpression of TGF-β(1), Smad2, 3, and 7, and VEGF-A in serum and bronchoalveolar lavage (BAL)...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Piotrowski, Wojciech J., Kiszałkiewicz, Justyna, Górski, Paweł, Antczak, Adam, Górski, Witold, Pastuszak-Lewandoska, Dorota, Migdalska-Sęk, Monika, Domańska-Senderowska, Daria, Nawrot, Ewa, Czarnecka, Karolina H., Kurmanowska, Zofia, Brzeziańska-Lasota, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595252/
https://ncbi.nlm.nih.gov/pubmed/26445225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0123-y
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