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Systematic Characteristic Exploration of the Chimeras Generated in Multiple Displacement Amplification through Next Generation Sequencing Data Reanalysis

BACKGROUND: The chimeric sequences produced by phi29 DNA polymerase, which are named as chimeras, influence the performance of the multiple displacement amplification (MDA) and also increase the difficulty of sequence data process. Despite several articles have reported the existence of chimeric seq...

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Veröffentlicht in:PLoS One
Hauptverfasser: Tu, Jing, Guo, Jing, Li, Junji, Gao, Shen, Yao, Bei, Lu, Zuhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595205/
https://ncbi.nlm.nih.gov/pubmed/26440104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139857
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