Interferon-β Modulates the Innate Immune Response against Glioblastoma Initiating Cells

Immunotherapy targeting glioblastoma initiating cells (GIC) is considered a promising strategy. However, GIC are prone to evade immune response and there is a need for potent adjuvants. IFN-β might enhance the immune response and here we define its net effect on the innate immunogenicity of GIC. The...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wolpert, Fabian, Happold, Caroline, Reifenberger, Guido, Florea, Ana-Maria, Deenen, René, Roth, Patrick, Neidert, Marian Christoph, Lamszus, Katrin, Westphal, Manfred, Weller, Michael, Eisele, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595134/
https://ncbi.nlm.nih.gov/pubmed/26441059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139603
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