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EGFR as a Target for Glioblastoma Treatment: An Unfulfilled Promise

The receptor for epidermal growth factor (EGFR) is a prime target for cancer therapy across a broad variety of tumor types. As it is a tyrosine kinase, small molecule tyrosine kinase inhibitors (TKIs) targeting signal transduction, as well as monoclonal antibodies against the EGFR, have been investi...

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Bibliographic Details
Published in:CNS Drugs
Main Authors: Westphal, Manfred, Maire, Cecile L., Lamszus, Katrin
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573763/
https://ncbi.nlm.nih.gov/pubmed/28791656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-017-0456-6
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