Alveolar macrophages support interferon gamma-mediated viral clearance in RSV-infected neonatal mice

BACKGROUND: Poor interferon gamma (IFNγ) production during respiratory syncytial virus (RSV) is associated with prolonged viral clearance and increased disease severity in neonatal mice and humans. We previously showed that intra-nasal delivery of IFNγ significantly enhances RSV clearance from neona...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Eichinger, Katherine M., Egaña, Loreto, Orend, Jacob G., Resetar, Erin, Anderson, Kacey B., Patel, Ravi, Empey, Kerry M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594958/
https://ncbi.nlm.nih.gov/pubmed/26438053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0282-7
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