Stimulation of Immature Lung Macrophages with Intranasal Interferon Gamma in a Novel Neonatal Mouse Model of Respiratory Syncytial Virus Infection

Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral death in infants. Reduced CD8 T-cells and negligible interferon gamma (IFNγ) in the airway are associated with severe infant RSV disease, yet there is an abundance of alveolar macrophages (AM) and neutrophils. However,...

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Detalhes bibliográficos
Main Authors: Empey, Kerry M., Orend, Jacob G., Peebles, R. Stokes, Egaña, Loreto, Norris, Karen A., Oury, Tim D., Kolls, Jay K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391240/
https://ncbi.nlm.nih.gov/pubmed/22792355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040499
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