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High Endogenous Expression of Chitinase 3-Like 1 and Excessive Epithelial Proliferation with Colonic Tumor Formation in MOLF/EiJ Mice

Colorectal cancer (CRC) development is mediated by uncontrolled survival and proliferation of tumor progenitor cells. Using animal models to identify and study host-derived factors that underlie this process can aid interventions in preventing tumor expansion and metastasis. In healthy steady states...

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發表在:PLoS One
Main Authors: Low, Daren, DeGruttola, Arianna K., Poltrak, Alexander, Mizoguchi, Atsushi, Mino-Kenudson, Mari, Mizoguchi, Emiko
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594921/
https://ncbi.nlm.nih.gov/pubmed/26440614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139149
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