Chitinase 3-Like-1 Expression in Colonic Epithelial Cells as a Potentially Novel Marker for Colitis-Associated Neoplasia

Chitinase 3-like-1 (CHI3L1/YKL-40) is a protein secreted from restricted cell types including colonic epithelial cells (CECs) and macrophages. CHI3L1 is an inflammation-associated molecule, and its expression is enhanced in persons with colitis and colon cancer. The biological function of CHI3L1 on...

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Bibliographic Details
Main Authors: Chen, Chun-Chuan, Pekow, Joel, Llado, Victoria, Kanneganti, Manasa, Lau, Cindy W., Mizoguchi, Atsushi, Mino-Kenudson, Mari, Bissonnette, Marc, Mizoguchi, Emiko
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2011
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157229/
https://ncbi.nlm.nih.gov/pubmed/21763261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.038
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