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IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc
BACKGROUND: The purpose of this study is to investigate IL-1β regulation of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS-4 and ADAMTS-5) expression through nuclear factor kappa B (NF-κB) in human nucleus pulposus (NP) cells. METHODS: qRT-PCR and Western blot were used to me...
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| Publicado no: | J Orthop Surg Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594913/ https://ncbi.nlm.nih.gov/pubmed/26438479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-015-0296-3 |
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