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Mesenchymal stromal cells loaded with paclitaxel induce cytotoxic damage in glioblastoma brain xenografts

INTRODUCTION: The goal of cancer chemotherapy is targeting tumor cells and/or tumor-associated microvessels with the lowest systemic toxicity. Mesenchymal stromal cells (MSCs) are promising vehicles for selective drug delivery due to their peculiar ability to home to pathological tissues. We previou...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Pacioni, Simone, D’Alessandris, Quintino Giorgio, Giannetti, Stefano, Morgante, Liliana, De Pascalis, Ivana, Coccè, Valentina, Bonomi, Arianna, Pascucci, Luisa, Alessandri, Giulio, Pessina, Augusto, Falchetti, Maria Laura, Pallini, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594910/
https://ncbi.nlm.nih.gov/pubmed/26445228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0185-z
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