Carrier-bound nonallergenic Der p 2 peptides induce IgG antibodies blocking allergen-induced basophil activation in allergic patients

BACKGROUND: More than 90% of house dust mite-allergic patients are sensitized to the major Dermatophagoides pteronyssinus allergen, Der p 2. The aim of this study was to develop and characterize an allergy vaccine based on carrier-bound Der p 2 peptides, which should allow reducing IgE- and T-cell-m...

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Detalhes bibliográficos
Publicado no:Allergy
Main Authors: Chen, K.-W., Focke-Tejkl, M., Blatt, K., Kneidinger, M., Gieras, A., Dall’Antonia, F., Faé, I., Fischer, G., Keller, W., Valent, P., Valenta, R., Vrtala, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594777/
https://ncbi.nlm.nih.gov/pubmed/22339348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1398-9995.2012.02794.x
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