Prophylactic and therapeutic vaccination with carrier-bound Bet v 1 peptides lacking allergen-specific T cell epitopes reduces Bet v 1-specific T cell responses via blocking antibodies in a murine model for birch pollen allergy

BACKGROUND: Vaccines consisting of allergen-derived peptides lacking IgE reactivity and allergen-specific T cell epitopes bound to allergen-unrelated carrier molecules have been suggested as candidates for allergen-specific immunotherapy. OBJECTIVE: To study whether prophylactic and therapeutic vacc...

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Main Authors: Linhart, B, Narayanan, M, Focke-Tejkl, M, Wrba, F, Vrtala, S, Valenta, R
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215111/
https://ncbi.nlm.nih.gov/pubmed/24447086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12216
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