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In vitro testing for diagnosis of idiosyncratic adverse drug reactions: Implications for pathophysiology
Idiosyncratic drug reactions (IDRs) represent a major health problem, as they are unpredictable, often severe and can be life threatening. The low incidence of IDRs makes their detection during drug development stages very difficult causing many post-marketing drug withdrawals and black box warnings...
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| Pubblicato in: | Br J Clin Pharmacol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley & Sons, Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594732/ https://ncbi.nlm.nih.gov/pubmed/25199801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12505 |
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