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In vitro testing for diagnosis of idiosyncratic adverse drug reactions: Implications for pathophysiology

Idiosyncratic drug reactions (IDRs) represent a major health problem, as they are unpredictable, often severe and can be life threatening. The low incidence of IDRs makes their detection during drug development stages very difficult causing many post-marketing drug withdrawals and black box warnings...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Elzagallaai, Abdelbaset A, Rieder, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594732/
https://ncbi.nlm.nih.gov/pubmed/25199801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12505
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