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Temporal transcriptional response to latency reversing agents identifies specific factors regulating HIV-1 viral transcriptional switch

BACKGROUND: Latent HIV-1 reservoirs are identified as one of the major challenges to achieve HIV-1 cure. Currently available strategies are associated with wide variability in outcomes both in patients and CD4(+) T cell models. This underlines the critical need to develop innovative strategies to pr...

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Foilsithe in:Retrovirology
Main Authors: Venkatachari, Narasimhan J., Zerbato, Jennifer M., Jain, Siddhartha, Mancini, Allison E., Chattopadhyay, Ansuman, Sluis-Cremer, Nicolas, Bar-Joseph, Ziv, Ayyavoo, Velpandi
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594640/
https://ncbi.nlm.nih.gov/pubmed/26438393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0211-3
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