Transcriptome analyses identify key cellular factors associated with HIV-1 associated neuropathogenesis in infected men

OBJECTIVE: HIV-1 viral proteins and host inflammatory factors have a direct role in neuronal toxicity in in vitro, however, the contribution of these factors in vivo in HIV-1 associated neurocognitive disorder (HAND) is not fully understood. We applied novel Systems Biology approaches to identify sp...

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Publicado no:AIDS
Main Authors: Venkatachari, Narasimhan J., Jain, Siddhartha, Walker, Leah, Bivalkar-Mehla, Shalmali, Chattopadhyay, Ansuman, Bar-Joseph, Ziv, Rinaldo, Charles, Ragin, Ann, Seaberg, Eric, Levine, Andrew, Becker, James, Martin, Eileen, Sacktor, Ned, Ayyavoo, Velpandi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389669/
https://ncbi.nlm.nih.gov/pubmed/28005686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001379
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