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Two-pore channel 1 interacts with citron kinase, regulating completion of cytokinesis

Two-pore channels (TPC1, 2, and 3) are recently identified endolysosmal ion channels, but remain poorly characterized. In this study, we show for the first time a role for TPC1 in cytokinesis, the final step in cell division. HEK 293 T-REx cells inducibly overexpressing TPC1 demonstrated a lack of p...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Horton, Jaime S, Wakano, Clay T, Speck, Mark, Stokes, Alexander J
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594595/
https://ncbi.nlm.nih.gov/pubmed/25665131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336950.2014.978676
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