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Urinary EGF Receptor Ligand Excretion in Patients with Autosomal Dominant Polycystic Kidney Disease and Response to Tolvaptan

BACKGROUND AND OBJECTIVES: Recent animal experiments suggest that dysregulation of the EGF receptor pathway plays a role in the pathophysiology of autosomal dominant polycystic kidney disease (ADPKD). Research on EGF receptor ligands in humans with ADPKD is lacking. EGF receptor ligands were measure...

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Publicado en:Clin J Am Soc Nephrol
Autores principales: Harskamp, Laura R., Gansevoort, Ron T., Boertien, Wendy E., van Oeveren, Wim, Engels, Gerwin E., van Goor, Harry, Meijer, Esther
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594078/
https://ncbi.nlm.nih.gov/pubmed/26231191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.09941014
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