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Simultaneous inference of haplotypes and alleles at a causal gene

We present a methodology which jointly infers haplotypes and the causal alleles at a gene influencing a given trait. Often in human genetic studies, the available data consists of genotypes (series of genetic markers along the chromosomes) and a phenotype. However, for many genetic analyses, one nee...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Larribe, Fabrice, Dupont, Mathieu J., Boucher, Gabrielle
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594033/
https://ncbi.nlm.nih.gov/pubmed/26500677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00291
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