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Single molecular force across single integrins dictates cell spreading

Cells’ ability to sense and interpret mechanical signals from the extracellular milieu modulates the degree of cell spreading. Yet how cells detect such signals and activate downstream signaling at the molecular level remain elusive. Herein, we utilize tension gauge tether (TGT) platform to investig...

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Detalhes bibliográficos
Publicado no:Integr Biol (Camb)
Main Authors: Chowdhury, Farhan, Li, Isaac T. S., Leslie, Benjamin J., Doğanay, Sultan, Singh, Rishi, Wang, Xuefeng, Seong, Jihye, Lee, Sang-Hak, Park, Seongjin, Wang, Ning, Ha, Taekjip
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593737/
https://ncbi.nlm.nih.gov/pubmed/26143887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ib00080g
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