Progestins Upregulate FKBP51 Expression in Human Endometrial Stromal Cells to Induce Functional Progesterone and Glucocorticoid Withdrawal: Implications for Contraceptive- Associated Abnormal Uterine Bleeding

Use of long-acting progestin only contraceptives (LAPCs) offers a discrete and highly effective family planning method. Abnormal uterine bleeding (AUB) is the major side effect of, and cause for, discontinuation of LAPCs. The endometria of LAPC-treated women display abnormally enlarged, fragile bloo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Guzeloglu Kayisli, Ozlem, Kayisli, Umit A., Basar, Murat, Semerci, Nihan, Schatz, Frederick, Lockwood, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593551/
https://ncbi.nlm.nih.gov/pubmed/26436918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137855
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