Long-acting progestin-only contraceptives impair endometrial vasculature by inhibiting uterine vascular smooth muscle cell survival

Molecular mechanisms responsible for abnormal endometrial vasculature in women receiving long-acting progestin-only contraceptives (LAPCs) are unknown. We hypothesize that LAPCs impair vascular smooth muscle cell (VSMC) and pericyte proliferation and migration producing thin-walled hyperdilated frag...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Kayisli, Umit A., Basar, Murat, Guzeloglu-Kayisli, Ozlem, Semerci, Nihan, Atkinson, Helen C., Shapiro, John, Summerfield, Taryn, Huang, S. Joseph, Prelle, Katja, Schatz, Frederick, Lockwood, Charles J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2015
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413279/
https://ncbi.nlm.nih.gov/pubmed/25847994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424814112
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