ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) are not primary resistance factors for cabazitaxel

INTRODUCTION: ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) proteins are efflux transporters that couple the energy derived from ATP hydrolysis to the translocation of toxic substances and chemotherapeutic drugs out of cells. Cabazitaxel is a novel taxane that...

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Vydáno v:Chin J Cancer
Hlavní autoři: Kathawala, Rishil J, Wang, Yi-Jun, Shukla, Suneet, Zhang, Yun-Kai, Alqahtani, Saeed, Kaddoumi, Amal, Ambudkar, Suresh V, Ashby, Charles R, Chen, Zhe-Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593353/
https://ncbi.nlm.nih.gov/pubmed/25962593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-015-0003-0
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