Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families

BACKGROUND: In family-based association analysis, each family is typically ascertained from a single proband, which renders the effects of ascertainment bias heterogeneous among family members. This is contrary to case–control studies, and may introduce sample or ascertainment bias. Statistical effi...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Med Genet
Auteurs principaux: Park, Suyeon, Lee, Sungyoung, Lee, Young, Herold, Christine, Hooli, Basavaraj, Mullin, Kristina, Park, Taesung, Park, Changsoon, Bertram, Lars, Lange, Christoph, Tanzi, Rudolph, Won, Sungho
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593209/
https://ncbi.nlm.nih.gov/pubmed/26286599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0198-6
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