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Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia

A key property of herpes simplex viruses (HSVs) is their ability to establish latent infection in sensory or autonomic ganglia and to reactivate on physical, hormonal, or emotional stress. In latently infected ganglia, HSVs express a long noncoding RNA, a latency-associated transcript (LAT), which p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shu, Minfeng, Du, Te, Zhou, Grace, Roizman, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593112/
https://ncbi.nlm.nih.gov/pubmed/26305977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1515369112
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