The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing

The precise assembly of inner ear hair cell stereocilia into rows of increasing height is critical for mechanotransduction and the sense of hearing. Yet, how the lengths of actin-based stereocilia are regulated remains poorly understood. Mutations of the molecular motor myosin 15 stunt stereocilia g...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Fang, Qing, Indzhykulian, Artur A, Mustapha, Mirna, Riordan, Gavin P, Dolan, David F, Friedman, Thomas B, Belyantseva, Inna A, Frolenkov, Gregory I, Camper, Sally A, Bird, Jonathan E
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592939/
https://ncbi.nlm.nih.gov/pubmed/26302205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08627
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