Attenuation of S. aureus-induced bacteremia by human mini-antibodies targeting the complement inhibitory protein Efb

Staphylococcus aureus (S. aureus) can cause a broad range of potentially fatal inflammatory complications (e.g. sepsis, endocarditis). Its emerging antibiotic resistance and formidable immune evasion arsenal have emphasized the need for more effective antimicrobial approaches. Complement is an innat...

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Vydáno v:J Immunol
Hlavní autoři: Georgoutsou-Spyridonos, Maria, Ricklin, Daniel, Pratsinis, Haris, Perivolioti, Eustathia, Pirmettis, Ioannis, Garcia, Brandon L., Geisbrecht, Brian V., Foukas, Periklis G., Lambris, John D., Mastellos, Dimitrios C., Sfyroera, Georgia
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592844/
https://ncbi.nlm.nih.gov/pubmed/26342032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500966
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