Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma

BACKGROUND: Recent evidence suggests that progesterone metabolites play important roles in regulating breast cancer. Previous studies have shown that tumorous tissues have higher 5α-reductase (5αR) and lower 3α-hydroxysteroid oxidoreductase (3α-HSO) and 20α-HSO activities. The resulting higher level...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lewis, Michael J, Wiebe, John P, Heathcote, J Godfrey
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC459223/
https://ncbi.nlm.nih.gov/pubmed/15212687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-4-27
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars