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Development of Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Indomethacin Disposition in Pregnancy
Findings of a recent clinical study showed indomethacin has lower plasma levels and higher steady-state apparent clearance in pregnant subjects when compared to those in non-pregnant subjects reported in separate studies. Thus, in the current work we developed a pregnancy physiological based pharmac...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4592215/ https://ncbi.nlm.nih.gov/pubmed/26431339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139762 |
| Oznake: |
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