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Evidence That the DNA Mismatch Repair System Removes 1-Nucleotide Okazaki Fragment Flaps

The DNA mismatch repair (MMR) system plays a major role in promoting genome stability and suppressing carcinogenesis. In this work, we investigated whether the MMR system is involved in Okazaki fragment maturation. We found that in the yeast Saccharomyces cerevisiae, the MMR system and the flap endo...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Kadyrova, Lyudmila Y., Dahal, Basanta K., Kadyrov, Farid A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591796/
https://ncbi.nlm.nih.gov/pubmed/26224637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.660357
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