The α(1)A-adrenergic receptor subtype mediates increased contraction of failing right ventricular myocardium

Dysfunction of the right ventricle (RV) is closely related to prognosis for patients with RV failure. Therefore, strategies to improve failing RV function are significant. In a mouse RV failure model, we previously reported that α(1)-adrenergic receptor (α(1)-AR) inotropic responses are increased. T...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Cowley, Patrick M., Wang, Guanying, Chang, Audrey N., Makwana, Om, Swigart, Philip M., Lovett, David H., Stull, James T., Simpson, Paul C., Baker, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Cardiovascular Neurohormonal Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591405/
https://ncbi.nlm.nih.gov/pubmed/26116709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00042.2015
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