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The α(1)A-adrenergic receptor subtype mediates increased contraction of failing right ventricular myocardium

Dysfunction of the right ventricle (RV) is closely related to prognosis for patients with RV failure. Therefore, strategies to improve failing RV function are significant. In a mouse RV failure model, we previously reported that α(1)-adrenergic receptor (α(1)-AR) inotropic responses are increased. T...

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Publicado en:Am J Physiol Heart Circ Physiol
Autores principales: Cowley, Patrick M., Wang, Guanying, Chang, Audrey N., Makwana, Om, Swigart, Philip M., Lovett, David H., Stull, James T., Simpson, Paul C., Baker, Anthony J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591405/
https://ncbi.nlm.nih.gov/pubmed/26116709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00042.2015
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