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Chronic antihypertensive treatment improves pulse pressure but not large artery mechanics in a mouse model of congenital vascular stiffness

Increased arterial stiffness is a common characteristic of humans with Williams-Beuren syndrome and mouse models of elastin insufficiency. Arterial stiffness is associated with multiple negative cardiovascular outcomes, including myocardial infarction, stroke, and sudden death. Therefore, identifyin...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Halabi, Carmen M., Broekelmann, Thomas J., Knutsen, Russell H., Ye, Li, Mecham, Robert P., Kozel, Beth A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591401/
https://ncbi.nlm.nih.gov/pubmed/26232234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00288.2015
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