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Evaluation of Two Novel (64)Cu-labelled RGD Peptide Radiotracers for Enhanced PET Imaging of Tumor Integrin α(v)β(3)

PURPOSE: Our goal was to demonstrate that suitably derivatized monomeric RGD peptide-based PET tracers, targeting integrin α(v)β(3), may offer advantages in image contrast, time for imaging, and low uptake in non-target tissues. METHODS: Two cyclic RGDfK derivatives, (PEG)(2)-c(RGDfK) and PEG(4)-SAA...

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Detalhes bibliográficos
Publicado no:Eur J Nucl Med Mol Imaging
Main Authors: Hernandez, Reinier, Czerwinski, Andrzej, Chakravarty, Rubel, Yang, Yunan, England, Christopher G., Graves, Stephen A., Nickles, Robert J., Valenzuela, Francisco, Cai, Weibo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591102/
https://ncbi.nlm.nih.gov/pubmed/26016906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3085-7
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