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Evaluation of Two Novel (64)Cu-labelled RGD Peptide Radiotracers for Enhanced PET Imaging of Tumor Integrin α(v)β(3)
PURPOSE: Our goal was to demonstrate that suitably derivatized monomeric RGD peptide-based PET tracers, targeting integrin α(v)β(3), may offer advantages in image contrast, time for imaging, and low uptake in non-target tissues. METHODS: Two cyclic RGDfK derivatives, (PEG)(2)-c(RGDfK) and PEG(4)-SAA...
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Publicado no: | Eur J Nucl Med Mol Imaging |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4591102/ https://ncbi.nlm.nih.gov/pubmed/26016906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3085-7 |
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