Transdermal Delivery of Small Interfering RNA with Elastic Cationic Liposomes in Mice

We developed elastic cationic liposomal vectors for transdermal siRNA delivery. These liposomes were prepared with 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) as a cationic lipid and sodium cholate (NaChol) or Tween 80 as an edge activator. When NaChol or Tween 80 was included at 5, 10, and 15%...

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Dettagli Bibliografici
Pubblicato in:J Pharm (Cairo)
Autori principali: Hattori, Yoshiyuki, Date, Masataka, Arai, Shohei, Kawano, Kumi, Yonemochi, Etsuo, Maitani, Yoshie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590792/
https://ncbi.nlm.nih.gov/pubmed/26555966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/149695
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