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Three-dimensional DEM–CFD analysis of air-flow-induced detachment of API particles from carrier particles in dry powder inhalers
Air flow and particle–particle/wall impacts are considered as two primary dispersion mechanisms for dry powder inhalers (DPIs). Hence, an understanding of these mechanisms is critical for the development of DPIs. In this study, a coupled DEM–CFD (discrete element method–computational fluid dynamics)...
Guardat en:
| Publicat a: | Acta Pharm Sin B |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4590728/ https://ncbi.nlm.nih.gov/pubmed/26579364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2013.11.003 |
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