TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen

BACKGROUND: A substantial proportion of cancer cases present with a metastatic tumor and require further testing to determine the primary site; many of these are never fully diagnosed and remain cancer of unknown primary origin (CUP). It has been previously demonstrated that the somatic point mutati...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Marquard, Andrea Marion, Birkbak, Nicolai Juul, Thomas, Cecilia Engel, Favero, Francesco, Krzystanek, Marcin, Lefebvre, Celine, Ferté, Charles, Jamal-Hanjani, Mariam, Wilson, Gareth A., Shafi, Seema, Swanton, Charles, André, Fabrice, Szallasi, Zoltan, Eklund, Aron Charles
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590711/
https://ncbi.nlm.nih.gov/pubmed/26429708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0130-0
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