Parkinsonian toxin-induced oxidative stress inhibits basal autophagy in astrocytes via NQO2/quinone oxidoreductase 2: Implications for neuroprotection

Oxidative stress (OS) stimulates autophagy in different cellular systems, but it remains controversial if this rule can be generalized. We have analyzed the effect of chronic OS induced by the parkinsonian toxin paraquat (PQ) on autophagy in astrocytoma cells and primary astrocytes, which represent...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Janda, Elzbieta, Lascala, Antonella, Carresi, Cristina, Parafati, Maddalena, Aprigliano, Serafina, Russo, Vanessa, Savoia, Claudia, Ziviani, Elena, Musolino, Vincenzo, Morani, Federica, Isidoro, Ciro, Mollace, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590600/
https://ncbi.nlm.nih.gov/pubmed/26046590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1058683
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