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Dual HER2 blockade in the neoadjuvant and adjuvant treatment of HER2-positive breast cancer
Human epidermal growth factor receptor 2 (HER2) is a tyrosine kinase transmembrane receptor that is overexpressed on the surface of 15%–20% of breast tumors and has been associated with poor prognosis. Consistently improved pathologic response and survival rates have been demonstrated with use of tr...
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| Veröffentlicht in: | Breast Cancer (Dove Med Press) |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Dove Medical Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4590321/ https://ncbi.nlm.nih.gov/pubmed/26451122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S90627 |
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