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Dual HER2 blockade in the neoadjuvant and adjuvant treatment of HER2-positive breast cancer

Human epidermal growth factor receptor 2 (HER2) is a tyrosine kinase transmembrane receptor that is overexpressed on the surface of 15%–20% of breast tumors and has been associated with poor prognosis. Consistently improved pathologic response and survival rates have been demonstrated with use of tr...

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Detalhes bibliográficos
Publicado no:Breast Cancer (Dove Med Press)
Main Authors: Advani, Pooja, Cornell, Lauren, Chumsri, Saranya, Moreno-Aspitia, Alvaro
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590321/
https://ncbi.nlm.nih.gov/pubmed/26451122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S90627
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