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Enhanced delivery of hydrophilic peptides in vitro by transdermal microneedle pretreatment
The aims of this study were to investigate the utility of solid microneedle arrays (150 µm in length) in enhancing transdermal delivery of peptides and to examine the relationship between peptide permeation rates and D(2)O flux. Four model peptides were used (Gly–Gln–Pro–Arg [tetrapeptide-3, 456.6 D...
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| Publicado no: | Acta Pharm Sin B |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4590292/ https://ncbi.nlm.nih.gov/pubmed/26579370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2013.12.011 |
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