Mice Deficient in AKAP13 (BRX) Are Osteoporotic and Have Impaired Osteogenesis

Mechanical stimulation is crucial to bone growth and triggers osteogenic differentiation through a process involving Rho and protein kinase A. We previously cloned a gene (AKAP13, aka BRX) encoding a protein kinase A-anchoring protein in the N-terminus, a guanine nucleotide-exchange factor for RhoA...

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Publicat a:J Bone Miner Res
Autors principals: Koide, Hisashi, Holmbeck, Kenn, Lui, Julian C, Guo, Xiaoxiao C, Driggers, Paul, Chu, Tiffany, Tatsuno, Ichiro, Quaglieri, Caroline, Kino, Tomoshige, Baron, Jeffrey, Young, Marian F, Robey, Pamela G, Segars, James H
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590282/
https://ncbi.nlm.nih.gov/pubmed/25892096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2534
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