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Postproliferative transcription of the rat osteocalcin gene is reflected by vitamin D-responsive developmental modifications in protein-DNA interactions at basal and enhancer promoter elements.

In the osteocalcin (OC) gene promoter, both independent positive and negative regulatory elements, as well as others with contiguous [TATA/glucocorticoid-responsive elements (GRE)] or overlapping [TATA/GRE, vitamin D-responsive enhancer elements (VDRE)/AP-1, and OC box/AP-1] domains, are sites for m...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Owen, T A, Bortell, R, Shalhoub, V, Heinrichs, A, Stein, J L, Stein, G S, Lian, J B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45902/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8381969/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1503
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