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MiRNA-mediated regulation of the SWI/SNF chromatin remodeling complex controls pluripotency and endodermal differentiation in human ES cells

MicroRNAs and chromatin remodeling complexes represent powerful epigenetic mechanisms that regulate the pluripotent state. miR-302 is a strong inducer of pluripotency, which is characterized by a distinct chromatin architecture. This suggests that miR-302 regulates global chromatin structure; howeve...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Wade, Staton L., Langer, Lee F., Ward, James M., Archer, Trevor K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589888/
https://ncbi.nlm.nih.gov/pubmed/26119756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2084
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