Pediatric cancer gone viral. Part II: potential clinical application of oncolytic herpes simplex virus-1 in children

Oncolytic engineered herpes simplex viruses (HSVs) possess many biologic and functional attributes that support their use in clinical trials in children with solid tumors. Tumor cells, in an effort to escape regulatory mechanisms that would impair their growth and progression, have removed many mech...

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Vydáno v:Mol Ther Oncolytics
Hlavní autoři: Friedman, Gregory K, Beierle, Elizabeth A, Gillespie, George Yancey, Markert, James M, Waters, Alicia M, Chen, Chun-Yu, Denton, Nicholas L, Haworth, Kellie B, Hutzen, Brian, Leddon, Jennifer L, Streby, Keri A, Wang, Pin-Yi, Cripe, Timothy P
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589754/
https://ncbi.nlm.nih.gov/pubmed/26436134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.16
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