Pediatric cancer gone viral. Part II: potential clinical application of oncolytic herpes simplex virus-1 in children

Oncolytic engineered herpes simplex viruses (HSVs) possess many biologic and functional attributes that support their use in clinical trials in children with solid tumors. Tumor cells, in an effort to escape regulatory mechanisms that would impair their growth and progression, have removed many mech...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Friedman, Gregory K, Beierle, Elizabeth A, Gillespie, George Yancey, Markert, James M, Waters, Alicia M, Chen, Chun-Yu, Denton, Nicholas L, Haworth, Kellie B, Hutzen, Brian, Leddon, Jennifer L, Streby, Keri A, Wang, Pin-Yi, Cripe, Timothy P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589754/
https://ncbi.nlm.nih.gov/pubmed/26436134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.16
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