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Bulged Invader probes: Activated duplexes for mixed-sequence dsDNA recognition with improved thermodynamic and kinetic profiles()

Double-stranded oligonucleotides with +1 interstrand zipper arrangements of intercalator-functionalized nucleotides are energetically activated for recognition of mixed-sequence double-stranded DNA. Incorporation of nonyl (C(9)) bulges at specific positions of these probes, results in more highly af...

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Détails bibliographiques
Publié dans:Chem Commun (Camb)
Auteurs principaux: Guenther, Dale C., Karmakar, Saswata, Hrdlicka, Patrick J.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589525/
https://ncbi.nlm.nih.gov/pubmed/26314212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc06264k
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